Anensefalus,The Worst disparity of congenital brain

Anensefalus is a situation where most of skull bone and brain is not formed. Anensefalus is a disparity of nerve tube ( a disparity happened in the early of development of foetus causing damage at brain former network and korda spinalis).

Anensefalus happened if nerve tube upside fails closes, but its(the cause is definitive unknown. research shows possibility that anensefalus to relate to poison in area of also acid contents folat which is low in blood.

Anensefalus found by 3,6-4,6 of 10000 newborn babies. risk factor the happening of anensefalus is:

history anensefalus at pregnancy before all

acid contents folat which low.

risk the happening of anensefalus can be lessened by the way of increasing minimum dosage folic acid of 3 month of before pregnancy and during kalends pregnancy.

Its(the symptom is:

1. mother : polihidramnion ( dilution fetal membrane in womb too much)

2. baby:

o doesn't have skull bone

o doesn't have brain ( hemisphere serebri and cerebellum)

o disparity at image of face

o heart disparity.

Inspection that is usually is done is:

- fat acid contents in pregnant mother serum

- amniosentesis ( to know existence of improvement of rate alfa-fetoprotein)

- rate alfa-fetoprotein increases ( shows existence of disparity of nerve tube)

- estriol rate at mother’s urine


Baby suffering anensefalus will not stay, they born in a state of dying or will die during a few days after bearing.